THE SULLIVAN LAB


 

"The more intelligent the question we ask of Mother Nature,

the more intelligent will be her reply."

-- Sir Charles Sherrington

 


 

WHAT DO WE DO?

 

We study the regulation of gene expression in a fascinating protozoan parasite

called Toxoplasma gondiiToxoplasma, a relative of the malarial parasite,

causes congenital birth defects, as well as opportunistic infection in AIDS,

cancer chemotherapy, and organ transplant patients.  There is also recent evidence suggesting

that this parasite is linked to neurological disorders, such as schizophrenia and behavior modification.

 

We hypothesize that the proteins controlling gene expression at epigenetic, transcriptional,

and translational levels may represent novel drug targets to fight Toxoplasma

and other infectious diseases.

 

Shown here are Toxoplasma parasites inside

human fibroblast cells

Follow the links below for more about...

Lab Tools & Resources

Publications & Dissertations

Personnel

 

**The Anti-Toxo Blog**

 

Breaking news...

We are currently looking for a few good postdocs - click here for details

 

Effective July 1, 2009, Dr. Sullivan will be promoted to Associate Professor with tenure.

 

Dr. Sullivan has been voted as Chair-elect of Division AA of the American Society for Microbiology.

 

Stacy Dixon, an MD/PhD student in Dr. Sullivan’s lab, was awarded a fellowship from the PhRMA Foundation (for 2009-11).

She was also the recipient of the 2008 K.K. Chen Award in Pharmacology and Toxicology.

 

Dr. Bradley Joyce, a postdoctoral fellow in Dr. Sullivan’s lab, was awarded a postdoctoral grant from the American Heart Association (12/2008).

 

Dr. Sullivan has been made a member of the editorial board for the journal Eukaryotic Cell for 2009-2012.

 

Dr. Bradley Joyce, a postdoctoral fellow in Dr. Sullivan’s lab, has been selected to speak at the Cold Spring Harbor Meeting on Translation Control in September, 2008.  Dr. Joyce presented findings that were recently published in the Journal of Biological Chemistry in an article entitled, “Translation Regulation by Eukaryotic Initiation Factor-2 Kinases in the Development of Latent Cysts in Toxoplasma gondii.”

 

Dr. Sullivan was a 2008 IUSM Trustee Teaching Award recipient.

 


WHERE ARE WE?

Indiana University School of Medicine

Dept of Pharmacology & Toxicology

IU Center For AIDS Research

IU Center of Environmental Health

635 Barnhill Drive, MS A-515

Indianapolis, IN 46202, USA

    317-278-9017 (lab)

 

   Click here for more about Indianapolis

 

CONTACT:   wjsulliv@iupui.edu                                      Last update:  June, 2009