THE SULLIVAN LAB

"The more intelligent the question we ask of Mother Nature,
the more intelligent will be her reply."
-- Sir Charles Sherrington
WHAT DO WE DO?
We study the regulation of gene expression in a fascinating protozoan parasite
called Toxoplasma gondii. Toxoplasma, a relative of the malarial parasite,
causes congenital birth defects, as well as opportunistic infection in AIDS,
cancer chemotherapy, and organ transplant patients. There is also recent evidence suggesting
that this parasite is linked to neurological disorders, such as schizophrenia and behavior modification.
We hypothesize that the proteins controlling gene expression at epigenetic, transcriptional,
and translational levels may represent novel drug targets to fight Toxoplasma
and other infectious diseases.

Shown here are Toxoplasma parasites inside
human fibroblast cells
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Breaking news...
We are currently looking for a few good postdocs - click here for details
Effective July 1, 2009, Dr. Sullivan will be promoted to Associate Professor with tenure.
Dr. Sullivan has been voted as Chair-elect of Division AA of the American Society for Microbiology.
Stacy Dixon, an MD/PhD student in Dr. Sullivan’s lab, was awarded a fellowship from the PhRMA Foundation (for 2009-11).
She was also the recipient of the 2008 K.K. Chen Award in Pharmacology and Toxicology.
Dr. Bradley Joyce, a postdoctoral fellow in Dr. Sullivan’s lab, was awarded a postdoctoral grant from the American Heart Association (12/2008).
Dr. Sullivan has been made a member of the editorial board for the journal Eukaryotic Cell for 2009-2012.
Dr. Bradley Joyce, a postdoctoral fellow in Dr. Sullivan’s lab, has been selected to speak at the Cold Spring Harbor Meeting on Translation Control in September, 2008. Dr. Joyce presented findings that were recently published in the Journal of Biological Chemistry in an article entitled, “Translation Regulation by Eukaryotic Initiation Factor-2 Kinases in the Development of Latent Cysts in Toxoplasma gondii.”
Dr. Sullivan was a 2008 IUSM Trustee Teaching Award recipient.
WHERE ARE WE?
Indiana University School of Medicine
Dept of Pharmacology & Toxicology
IU Center of Environmental Health
635 Barnhill Drive, MS A-515
Indianapolis, IN 46202, USA
317-278-9017 (lab)

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CONTACT: wjsulliv@iupui.edu Last update: June, 2009